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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRPV5
All Species:
23.33
Human Site:
T366
Identified Species:
46.67
UniProt:
Q9NQA5
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQA5
NP_062815.2
729
82551
T366
R
T
H
S
R
D
I
T
I
L
Q
Q
K
L
L
Chimpanzee
Pan troglodytes
XP_519444
729
82502
T366
R
T
H
S
R
D
I
T
I
L
Q
Q
K
L
L
Rhesus Macaque
Macaca mulatta
XP_001089988
729
82599
T366
R
T
H
S
R
D
I
T
I
L
Q
Q
K
L
L
Dog
Lupus familis
XP_539860
808
91760
T442
R
T
D
P
R
D
N
T
V
L
Q
Q
K
L
L
Cat
Felis silvestris
Mouse
Mus musculus
P69744
723
82199
T359
R
T
H
V
R
D
N
T
I
M
E
Q
K
S
L
Rat
Rattus norvegicus
Q9JIP0
723
82435
T359
R
T
H
V
R
D
N
T
V
L
E
Q
K
P
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518104
356
39437
E32
A
A
P
D
L
V
T
E
P
M
T
S
D
L
Y
Chicken
Gallus gallus
XP_416530
724
82934
T368
K
T
S
S
R
D
N
T
V
Y
V
Q
K
M
L
Frog
Xenopus laevis
NP_001082336
674
75844
P334
L
L
E
S
Y
N
Y
P
M
D
E
L
H
L
V
Zebra Danio
Brachydanio rerio
NP_001001849
707
80910
H362
Y
T
K
A
G
N
D
H
T
I
K
I
K
K
T
Tiger Blowfish
Takifugu rubipres
NP_001027938
719
81679
H368
Y
T
K
S
E
L
D
H
T
I
R
V
Q
K
T
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q6AWW5
524
56905
A200
G
Q
T
A
L
H
M
A
V
K
G
Q
N
T
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
96.8
78.4
N.A.
80.6
79.9
N.A.
34.7
68.7
50.8
46.9
51.7
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
98
83.2
N.A.
88.8
89
N.A.
40.5
82.9
66.6
68.5
69.2
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
73.3
N.A.
66.6
66.6
N.A.
6.6
53.3
13.3
13.3
13.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
80
N.A.
80
80
N.A.
13.3
73.3
40
40
33.3
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
17
0
0
0
9
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
9
0
59
17
0
0
9
0
0
9
0
0
% D
% Glu:
0
0
9
0
9
0
0
9
0
0
25
0
0
0
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
0
0
9
0
0
0
0
0
9
0
0
0
0
% G
% His:
0
0
42
0
0
9
0
17
0
0
0
0
9
0
0
% H
% Ile:
0
0
0
0
0
0
25
0
34
17
0
9
0
0
0
% I
% Lys:
9
0
17
0
0
0
0
0
0
9
9
0
67
17
0
% K
% Leu:
9
9
0
0
17
9
0
0
0
42
0
9
0
50
59
% L
% Met:
0
0
0
0
0
0
9
0
9
17
0
0
0
9
0
% M
% Asn:
0
0
0
0
0
17
34
0
0
0
0
0
9
0
0
% N
% Pro:
0
0
9
9
0
0
0
9
9
0
0
0
0
9
0
% P
% Gln:
0
9
0
0
0
0
0
0
0
0
34
67
9
0
0
% Q
% Arg:
50
0
0
0
59
0
0
0
0
0
9
0
0
0
0
% R
% Ser:
0
0
9
50
0
0
0
0
0
0
0
9
0
9
0
% S
% Thr:
0
75
9
0
0
0
9
59
17
0
9
0
0
9
17
% T
% Val:
0
0
0
17
0
9
0
0
34
0
9
9
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
17
0
0
0
9
0
9
0
0
9
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _